Sunday, January 22, 2017

Blog 1: American Association of Poison Control Centers

http://www.bvascientific.com/content.aspx?file=customerpages/clinical-toxicology-providing-vital-data-in-poisoning-cases.htm
The American Association of Poison Control Centers (AAPCC) works with multiple poison control centers all over the country to help gather data on poisonings and their causes. To reach the AAPCC you can call 1-800-222-1222. There are eight alerts that the American Association Poison Control Centers lists. These eight are bath salts, current annual highlights (which will be broken down and explained later), e-cigarettes, food poisoning, hand sanitizer, laundry detergent packets, opioid medications, and synthetic cannabinoids. These alerts were compiled from the 2.9 million calls received by the AAPCC in 2014. 50 percent of the people that were exposed were children younger than six and older with the next highest groups being adults between the ages of 20 and 59 that were exposed at 28 percent, adults 60 and older as well as teenagers both were exposed at the eight percent, and finally children ranging in ages six to 12 rounded out the distribution at six percent. These would match with some of the alerts since most young kids like to stick whatever they can find in their mouths so things like hand sanitizer and laundry detergent packets would be one of the reasons these young children could poisoned. Also adults 20-59 are maturing and going from experimenting with e-cigarettes and synthetic cannabinoids in college which can both be very poisonous; to when they first start to take prescription drugs as they age would lead to possible overdose of the opioid medications. The statistics support these claims because 79 percent of exposures are unintentional, and 79 percent of the routes of exposures are ingestion. The other routes of exposure are dermal at seven percent, inhalation at six percent, ocular at four percent, and bites/sting and other/unknown both at two percent. The other reasons for exposure are intentional at 17 percent, and adverse reaction and unknown/other both at two percent.
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All of these reasons is why the people answering the phone at poison control are either doctors, nurses, or pharmacists so that the person has the knowledge to quickly help those calling. 71 percent of those calling because of exposure are calling from home while 21 percent are calling from a health care facility and just eight percent are calling from a school, workplace, or unknown location. 75 percent of the calls are exposures from humans meaning humans are the cause of the poisoning. 23 percent of the calls into the center are questions about medications meaning no one is exposed to anything. Rounding out this list would be the two percent that calling due to exposure from an animal/insect sting or bite. In the top 10 exposure categories by each age group analgesics come within the top three of each age group. The top 10 exposures for all human exposures rank in the following order: analgesics, cosmetics, household cleaning substances, 
sedative/hypnotics/antipsychotics, antidepressants, antihistamines, cardiovascular drugs, foreign bodies/toys, pesticides, and topical preparations. Pediatric exposures top 10 is: cosmetics, household cleaning substances, analgesics, foreign bodies/toys, topical preparations, vitamins, antihistamines, pesticides, gastrointestinal preparations, plants. Adult exposures top 10 is: analgesics, sedative/hypnotics/antipsychotics, antidepressants, cardiovascular drugs, household cleaning substances, alcohols, anticonvulsants, pesticides, bites and envenomation, and antihistamines. There is a lot of overlap in all these lists which would help to support the data from the route and reason for exposure graphs because most of these would have to be ingested and especially in the pediatric category they would be ingested unintentionally. 

These alerts and top 10 substances can all be very dangerous, so it is a good thing that there is a number people can call to get help they need to potentially save their life or the life of a loved one. A website like AAPCC is also helpful for people who are studying toxicology because it gives them a resource to see the current problems to study further.  
https://toxlearn.nlm.nih.gov/htmlversion/images/3_2_pills.jpg